Sakura is just a normal fourth grader attending Tomoeda Elementary School. One day after school, she finds a mysterious book in her father's library called "The Clow". When she touches it, mysterious cards fly out, an a strange creature name Kero comes out. He reveals to her that now, she must re-capture all the cards, or else the world could be in serious trouble.

Sakura has captured the Fly card but is still reluctant to take on the role of the Cardcaptor in spite of Cerberus's encouragement. However Sakura has yet to find that she has an adoring fan who will support her calling as the Cardcaptor. Furthermore there's a Clow card causing havoc at the school.

Sakura's class is on a field trip to the aquarium. During the penguin show, something catches the trainer's leg and a penguin and pulls them into the water, but they are saved by Sakura's brother, Toya, who is working part-time there. At school, Tomoyo gives Sakura and Kero mobile phones and on the way home, Sakura bumps into Yukito who invites her on a casual "date" to the aquarium. While they are eating, the Watery Card attempts to drown Sakura. For the first time, Sakura has to formulate a plan to capture a card.

While cleaning the house, Sakura finds two dormant Clow Cards, the Wood and the Rain. But while running an errand for her father, the two cards activate creating a jungle inside the house.

The new stores Twin Bells opens and everyone goes to check out its various cute merchandise. While Sakura and her friends are looking around the store, Chiharu shows up and buys a stuffed Panda. Everyone heads to her house, but suddenly the Panda disappears. Sakura brings Kero to the shop where he senses a Clow Card.

When Naoko tells her friends about something mysterious she saw in the woods behind Tomoeda Elementary, Chiharu, Rika, Naoko, Tomoyo and an afraid Sakura are going to investigate. When they see strange things, Sakura brings Kero to investigate to see if a Clow Card is nearby.

Sakura is at the museum when she sees a boy about to slash a painting. Before he can do it, everything goes Silent and they wind up somewhere else. Sakura tells Kero about it and he realizes it is the Silent card. Sakura must now sneak into the museum quietly to capture it, a task easier said then done.

Sakura keeps dreaming of a boy, who then ends up transferring to her class! The boy is named Shaoran Li and he wants to take the Clow Cards from Sakura. Before he can do that Touya shows up to protect Sakura. That night Sakura goes after the Thunder Card, and Li appears to get the card as well.

Sakura is still upset over Syaoran's comments from the other night. To cheer her up, Rika and Tomoyo take Sakura to a shop and the three of them each buy their own brooch. When Rika puts her own, she is possessed by the Sword Card and starts attacking Sakura.

Sakura's school is having a field day and Sakura and her family is truly enjoying themselves. That is, until a Clow Card appears and interrupts a competitive race!

Sakura is invited to Tomoyo's home for the first time. She is shocked to find Tomoyo's house to be an elaborate mansion complete with its own maids. Tomoyo presents a special chest and explains the key to the box bounces out whenever she tries to open it. Kero senses it's the work of a Clow Card!

Sakura, Kero and Syaroan discover time is caught in a loop and that the same day is repeating over and over and over again. It's time for Sakura to take action and capture this time-meddling Clow Card!

Sakura's class is visiting the zoo for a field trip and her group is assigned to observe the elephants. Near noon, something begins to break open the cages causing chaos among the visitors and Kero is positive it's a Clow Card.

Sakura is invited to her brother's high school culture festival. She meets Tomoyo and Syaoran there and catches a play by Yukito and Toya's class. During the play, a mist forms outside the auditorium and enters through the vents where it destroys the stage and puts Toya and a girl named Yoko in danger.

Syaoran captures his second Clow Card after defeating the Storm card. Kero and Sakura blame each other for failing to catch the card, and the tension between them develops into a huge fight.

Sakura's family and Yukito takes a vacation to the country side, where Sakura meets a kind old man. The old man mentions his deceased granddaughter, and how much Sakura reminds him of her. As thanks for spending time with him, the man hands Sakura a present. Soon the vacation ends and Sakura has to go home, but not without leaving a little present of her own.

Sakura and her class is on a trip to the beach for a few days. On the first night, Naoko tells one of her scary story causing Sakura to flee to the teacher's lodging, but she is found by Syaoran who senses something in a cave nearby. Together at the beach, the two have their first civil conversation where Syaoran tells Sakura about Wei Wang, his legal guardian. In a test of courage, the students are sent into the cave to place a candle at the shrine. However, all of them save Sakura and Syaoran disappear.

Sakura visits a festival with Tomoyo, Yukito, and Toya. After meeting Chiharu and Takashi, Sakura and Yukito wander away from the group where they find glowing lights falling from a tree like snow at the back of the shrine—just like a dream Sakura envisioned the night before.

The summer holidays are coming to an end and Sakura still has a lot of homework to do. Making a deal with her brother and Kero to help her, Sakura is left with only a book report to do, and meets with Tomoyo at the library. There, they meet Syaoran who refuses to share a library cubicle. Sakura needs a specific book to do her report on, as does Syaoran. When the Move Card steals it and teleports the book around, Sakura and Syaoran give chase.

Sakura properly meets Meiling, who openly reveals she and Syaoran are engaged. Meiling, aggressive and bratty, takes a disliking to Sakura, believing she is Syaoran's rival. At home, Sakura learns a mysterious woman is challenging people to fights. Worried this woman could target Toya, Sakura searches for her.

During a school race, Meiling is determined to win with Syaoran, in their usual "One-Two Finish" they were known for in their previous school. During the race, both Syaoran and Sakura take off at top speed after seeing that Yukito is watching. As the run, the Loop card causes traps Sakura and Syaoran, causing them to run in circles. After they realize what has happened, Sakura is able to use the Sword card to cut the loop. Syaoran carries Meiling, who hurt her ankle, the rest of the way to the finish line, joined by Sakura.

Sakura's father has an important presentation to complete so Sakura and her brother decide to help by taking on all the chores around the house. Sakura decides to do more and brings a snack for her father at the university. While she is there, the Sleep card shows up and starts to make all the students and professors fall asleep. Sakura manages to capture the card with the help of Windy, however her father's laptop is ruined in the process. Although her father forgives her, Sakura still feels guilty so her father deicides to make her his personal assistant and they eventually get the presentation finished.

A rumor spreads at Sakura's school that a ghost haunts the music room and sings at night. At first afraid to investigate, Sakura changes her mind when Yukito comments he would like to hear the ghost sing. Joined by Tomoyo, Kero, Syaoran, and Meiling, Sakura learns the ghost is the Song Card, and the voice she is impersonating is Tomoyo's.

When Tomoyo comes over to measure Sakura for a new outfit, Sakura comes in contact with the Little Card, which shrinks her and her magic. While Tomoyo and Kero search for her, Sakura winds up in the backyard, chased by the local wildlife.

Numerous people accuse Sakura of causing trouble around town. Sakura is in denial until she spots her doppelganger. Using the Clow Cards, Sakura identifies her twin as a Clow Card. She also learns that all the cards know her identity. Realizing the card is targeting Toya, Sakura goes to find him.

On her way home from school, Sakura meets a mysterious woman. At school, this woman, Kaho Mizuki, is introduced as the class' substitute maths teacher. Syaoran becomes suspicious of Ms. Mizuki, who he senses has strong magical powers. While at the local shrine, Sakura and her friends are trapped within the walls of the Maze Card. They are unable to escape, and Meiling is separated from the others.

Sakura learns that Toya knew Ms. Mizuki whilst in junior high. She later meets Ms. Mizuki at the shrine, learning she lives there. Sakura, Kero, and Syaoran later visit the shrine upon sensing a Clow Card, but nothing appears. Sakura and Syaoran both come to terms that they both like Yukito. Sakura is suddenly sucked into the shrine's tree by the Return Card. Sakura finds herself experiencing events from the past between Toya and Ms. Mizuki.

A new craze sweeps Twin Bells, specifically collectible luck cards which resemble the Clow Cards. Meiling nonchalantly tries to buy a romance card to woo Syaoran, but ends up buying the dangerous Shot Card instead.

Sakura practices in the kitchen with her father for an upcoming home-economics class. Sakura's classmates decide they will bake cakes. The following day, everyone begins making their various cakes, but after leaving them to bake over lunch, they come back to find them to be far too sweet. The next day, everyone starts over and make sure they measure the ingredients correctly. Sakura and Syaoran sense a Clow Card, staying behind over lunch to find it.

Sakura's attempt to capture the speedy Dash Card fails. The injured, fox-like spirit ends up in the care of Sakura's upperclassman, Rei, who is on the track team. The Dash increases Rei's agility as a way of thanks. Sakura becomes reluctant to capture it, due to Rei's relationship with it.

Naoko, Sakura's classmate and friend, goes to a bookstore and buys a mysterious book which has no title and the things she writes in it comes to life. Sakura catches the card which appears to be the Create card by using the newly captured Big to enlarge her size and seal the dragon she encountered away.

During the capture of the Change Card, Syaoran and Kero pin it down so Sakura can catch it. However, the two discover they have swapped bodies thanks to the Change. The process will reverse after twenty-four hours, but only if Syaoran and Kero are touching each other in the place the spell was cast. Both blunder their way through the day, pretending to be each other.

Sakura’s fourth grade class takes a trip to the town’s ice skating rink. At the ice skating rink, the students begin to feel low, freezing temperatures due to the Freeze card. Eventually, the Freeze card beings to freeze everyone by covering them with ice, except those with magical powers, which include Sakura, Syaoran, and Ms. McKenzie, who was hiding near the back of the rink during Freeze’s appearance. With the help of Syaoran’s distractions, Sakura is able to capture the Freeze card into a clow card and ultimately, Syaoran became the master of the Freeze card due to his idea of getting Freeze to appear out of the ice rink.

Sakura and Yukito participate as a two people team in the quiz tournament. As they get to the 10th question which is the last, Ms. Mizuki warns them about the full moon tonight. They go in the forest and then suddenly Sakura becomes dazed and begins to fall off the cliff. Yukito dashes to Sakura and covers her while his leg becomes injured.

Christmas is coming, which is also Yukito's birthday, but Sakura is unsure what to get him. She asks Meilin for advise who tells her it can anything because if the person likes her they will like the gift. Sakura asks Yukito to go to the amusement park with her, using tickets given to her by Chiharu. Tomoyo and Kero follow them to film Sakura's "date". Sakura and Yukito run into Syaoran and Meilin. While they are at a cafe, the Firey card appears. Syaoran uses the Time card, giving Sakura time to use Sleep and put everyone at the park asleep. She then tries to capture Firey using Windy, but Firey is a strong attack card and Windy is unable to defeat it. Sakura has to use two elemental cards, Watery and Windy, together in order to capture Firey. With Firey captured, Kero regains a small amount of his power, enabling him to make small fires. Sakura gives Yukito his Christmas present: a doll of himself.